Fuente: New England Journal of Medicine
Expuesto el: miércoles, 05 de mayo de 2010 22:56
Autor: Jin, Y., Birlea, S. A., Fain, P. R., Gowan, K., Riccardi, S. L., Holland, P. J., Mailloux, C. M., Sufit, A. J. D., Hutton, S. M., Amadi-Myers, A., Bennett, D. C., Wallace, M. R., McCormack, W. T., Kemp, E. H., Gawkrodger, D. J., Weetman, A. P., Picardo, M
Asunto: Variant of TYR and Autoimmunity Susceptibility Loci in Generalized Vitiligo
The results of a genomewide association study of generalized vitiligo implicate genes involved in the immune response and also a variant of TYR, which encodes tyrosinase. This variant of TYR encodes a protein that seems particularly likely to be detected by immune surveillance. |